Recombinant probiotic-Based Vaccines; Attractive vehicles for immunization via mucosal routes

نویسندگان

  • Nabizadeh, Seyyed Fatemeh Department of Medical Laboratory Sciences, School of Medicine, Islamic Azad University of Kazerun, Kazerun, Iran.
  • Dehqan, Fatemeh Department of Medical Laboratory Sciences, School of Medicine, Islamic Azad University of Kazerun, Kazerun, Iran.
چکیده مقاله:

Introduction: The importance of genetically modified microorganisms, including probiotics, now widely have considered as attractive vehicles for mucosal delivery of therapeutic molecules. Previous studies have indicated that mucosal administration of these molecules can effectively trigger humoral along with cellular immune responses. Therefore, development of induction of mucosal immune responses, utilizing of recombinant probiotics-based vaccines, as live delivery vectors with no side effects in humans, may contribute to effectiveness of control strategies against infection agents.  

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عنوان ژورنال

دوره 30  شماره 4

صفحات  4702- 4705

تاریخ انتشار 2022-07

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